Shoaie et al. describe a computational platform designed to elucidate the complex metabolic interactions between gut microbes, host, and diet. The model predictions are validated in humans and reveal how microbial gene richness and diet affect gut microbiota composition, as well as amino acid and SCFA levels.

 

Highlights:

http://www.cell.com/cell-metabolism/abstract/S1550-4131(15)00330-7 

Cell Metabolism, Volume 22, Issue 2, p320–331

Authors:

Saeed Shoaie, Pouyan Ghaffari, Petia Kovatcheva-Datchary, Adil Mardinoglu, Partho Sen, Estelle Pujos-Guillot, , Catherine Juste, Salwa Rizkalla, Julien Chilloux, Lesley Hoyles, Jeremy K. Nicholson, MICRO-Obes Consortium, Joel Dore, Marc E. Dumas, Karine Clement, Fredrik Bäckhed, Jens Nielsen

Correspondence:
This email address is being protected from spambots. You need JavaScript enabled to view it.

DOI: http://dx.doi.org/10.1016/j.cmet.2015.07.001 

Our site uses cookies. We'll assume that you are OK with this if you browse further. To find out more about the cookies we use, see our Cookie Policy.

I accept cookies from this site